Vector Control, Saving Lives

WHO recommends Syngenta's new long-lasting insecticide formulation

Syngenta and IVCC collaboration delivers new longlasting insecticide formulation, Actellic® 300CS, now recommended by the World Health Organization to fight insecticide resistant mosquitoes

26 November 2013

Syngenta and IVCC are proud to announce that The World Health Organization Pesticide Evaluation Scheme (WHOPES) has granted a formal recommendation for the use of Actellic® 300CS in malaria vector control. The WHO recommendation opens up additional opportunities for more malaria control programs around the world to access this new long lasting insecticide formulation designed for the control of pyrethroid resistant mosquitoes.

Syngenta believes that people deserve to live their lives uninterrupted by mosquitoes and the diseases that they can transmit. Syngenta has a rich pipeline of insecticides and access to advanced delivery technologies and consequently has been providing leading edge solutions on mosquito control for decades.

Mosquitoes have evolved to survive a number of the existing control products and this threatens the effectiveness of disease prevention programs. IVCC is a product development partnership committed to working with industrial partners to accelerate the development and introduction of new tools to meet these challenges. Syngenta and IVCC have had a long standing collaboration to accelerate and enrich the innovation pipeline for mosquito control.

The development of Actellic 300CS was initiated in 2007, not only to control resistance to the pyrethroid class of chemistry, but also deliver longer lasting performance to facilitate greater program efficiency in spraying programs. Since then, the WHO Global Plan for Insecticide Resistance Management recommends the deployment of non pyrethroid products when programs are looking for technology to complement mass distribution of long lasting insecticide treated mosquito nets.

Syngenta used their expertise in microencapsulation technology to create Actellic 300CS, which is designed specifically for residual spraying. Numerous independent trials have demonstrated at least 9 months residual performance on a range of household surfaces, a significant improvement over current alternatives. Trials have also demonstrated control of pyrethroid resistant strains in both Anopheles and Culex species of mosquitoes.

This unique combination of controlling pyrethroid resistance with proprietary long lasting technology provides the opportunity for malaria control program managers have a greater impact on malaria as part of their integrated control program. Long lasting performance allows for reduction of spray program costs through moving to just one application per season whilst also managing pyrethroid resistance. This is essential when long lasting insecticide treated nets are currently dominated by this class of chemistry.

Actellic 300CS is the first commercial product to exit the IVCC pipeline, and this important WHO recognition meets one of Syngenta [MSB1] and IVCC’s commitments to provide access to new technology in disease endemic countries. More than a million people are now estimated to be protected by Actellic 300CS and production has been scaled up to support all key markets.

This development is just one step on the journey to develop new solutions to controlling mosquito-borne disease, and more alternatives are urgently needed, especially in the fight against growing insecticide resistance. Syngenta and IVCC continue to collaborate on the development of the next generation of insecticides, which will provide a robust solution to future insecticide resistance and equip malaria control programs with the tools they need to defeat malaria.

For more information on Actellic 300CS or Syngenta products please contact: vector [dot] control [at] syngenta [dot] com


Footnote: Actellic is a registered trademark of the the Syngenta Group companies

 [MSB1]This is one of our commitments too as part of the Global Access Plan

 Syngenta and IVCC collaboration deliver new longlasting insecticide formulation, Actellic® 300CS, now recommended by the World Health Organization to fight insecticide resistant mosquitoes