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Reality of Rotation of Insecticdes

30th May 2018
Chris Larkin
Reality of Rotation of Insecticdes

Rotation of 3GIRS insecticides in full swing

Unitaid, IVCC and Sumitomo Chemical Company announced the inclusion of the new insecticide SumiShield® 50WG, as part of the NgenIRS project. This announcement followed the prequalification listing by WHO in October 2017.

With two long-lasting IRS (3GIRS) products now available, SumiShield® 50WG and Actellic® 300CS, the pre-emptive annual rotation goal outlined in the Global Plan for Insecticide Resistance

Management in malaria vectors (GPIRM) is achievable. Bayer’s 3GIRS product, Fludora® Fusion is currently undergoing final stage trials required for WHO prequalification and we hope this 3rd long lasting product can join the NgenIRS programme in 2019. BASF´s Sylando® 240SC is under WHO-evaluation.

Funders and procurers now have the opportunity to simultaneously prevent resistance build up and affect the cost-effectiveness of IRS by adopting pre-emptive, subnational rotation strategies where appropriate. Rotating all effective and available insecticides is key as a wholesale shift from one effective long-lasting IRS product to another within the market would undermine the goals of increasing competition, reducing product cost, and the market volatility of IRS products. Experts have proposed a new strategic approach based on pre-emptive rotation of multiple 3GIRS products within a country to:

  • support resistance prevention best practices;
  • support stable, multi-year forecasts and
  • support reduced price through competition.

Half of the NgenIRS partner countries adopted a sub-national rotation strategy for 2018, as part of their national insecticide resistance management plan. Tanzania has completed their IRS sub-national rotation campaign for 2018, Ghana and Burkina Faso are in the process of adopting this strategy and the remaining four countries will follow.

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