Between 2011 and 2018, five GLP training workshops have been held (1 in the UK and 4 in Africa). Ongoing mentoring has been given on QMS development, including the development of SOPs.
To date, two of the research facilities in Africa have been granted GLP certification by the South African National Accreditation System (SANAS): the PAMVERC–KCMUCo facility in Moshi, Tanzania and the CREC/LSHTM facility in Cotonou, Benin. The five remaining facilities are progressing well towards full GLP compliance and are expected to become GLP certified during the next 12 months.
The eight collaborating research facilities being supported by IVCC towards GLP certification form part of a larger network of collaborating trials facilities in Africa that help IVCC and our industrial partners to assess cross-resistance risk to Active Ingredients (AIs) and to evaluate the performance of prototype and final products. This includes laboratory trials using well-characterised insecticide susceptible and resistant strains of several Anopheline malaria vector species, semi-field cage trials, small-scale experimental hut trials and community village-scale trials.
Although much of the current focus of product testing is on the evaluation of Long Lasting Insecticidal Nets (LLIN) and Indoor Residual Spraying (IRS) formulations, IVCC’s network of collaborating trials facilities can also evaluate other types of vector control products including Attractive Targeted Sugar Baits (ATSB®), larvicides, and topical and spatial repellents. For some of the collaborating facilities that are not part of the GLP project, IVCC is providing advice on the development of quality management systems to help assure the generation of reliable data.